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Rotor syndrome, also known as Rotor type hyperbilirubinemia, is a rare inherited disease that affects the liver, causing a buildup of a yellow pigment called bilirubin in the blood

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After reviewing literature and conducting a two-round Delphi survey with 42 experts, a consensus emerged that emphasizes prioritizing clinical symptoms in diagnosis, with serum B12 as a screening marker supported by methylmalonic acid or homocysteine levels for additional confirmation

We used our model for APAP metabolism, integrated with our model for GSH metabolism[9] to compute the concentration of hepatic GSH and the amount of covalent binding of NAPQI after various doses of APAP