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In the SELECT trial , semaglutide 2.4 mg was associated with an average weight loss of nearly 10% over two years in adults with overweight or obesity who also had heart disease

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As demand increases for GLP-1 medications, replicating the rigorous weight monitoring protocols used in clinical trials can be challenging

For example, in this study, liraglutide helped people lose almost 13 pounds more than a placebo over 1 year, and over 2 years, it reduced the prevalence of prediabetes by 52% and metabolic syndrome by 59%