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Because of the unknown potential for serious adverse reactions in the breastfed infant due to the possible accumulation of SNAC, and because there are alternative semaglutide products that do not contain SNAC that can be used during lactation, advise patients that breastfeeding is not recommended during treatment with RYBELSUS or OZEMPIC tablets

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To enable choices to be made regarding treatment for SANS cases, it is important that future studies use clinically relevant outcomes of direct measures of changes observed in SANS, such as optic disc oedema and visual acuity, rather than surrogate markers such as intraocular pressure and jugular vein volume

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