E N D Presentation Transcript INCRETINS Glucagon-like Peptide 1 (GLP-1)and Glucose-Dependent Insulinotrophic Polypeptide (GIP) account for ~90% of the incretin effect In response to equivalent hyperglycemic stimuli, ORAL glucose elicits a greater insulin response than IV glucose Insulin Glucose-Stimulated Secretion of Insulin Glucose GLUT2 Pancreatic Cell SUR Glucose Potassium channel GK K+ Pyruvate GLP-1 ATP + ATP GIP TCA Cycle* AC + Calcium channel cAMP [Ca2+] Amplifying Triggering AC = adenylyl cyclase
BPC-157 is derived from gastric juice proteins and studied for tissue healing
3 In the Framingham data cohort of patients with HF (n=6,340), a higher proportion of women had HFpEF compared to men in whom heart failure with reduced ejection fraction (HFrEF) was the predominant phenotype
The following are our recommended vitamin B12 injection needle size and gauge: B12 Shots Needle Size (Length) For subcutaneous B12 injections, we suggest using shorter 4-5mm needles
There are still no studies looking at how inulin affects GLP-1 in the body and whether or not it would be a reliable weight loss supplement
Keep in mind, too, cold sores can spread to other parts of the body