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ROS are involved in damaging cellular components such as lipids, proteins, and DNA, leading to oxidative stress, which has an adverse effect on the growth and development of plants

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Receptor activation leads to activation of the IB kinase complex, which results in phosphorylation and ubiquitination degradation of the IB protein, ultimately activating NF-B

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The active site was identified based on the binding site of ethacrynic acid, a known GSTP1 inhibitor