A 2016 review of 2 randomized clinical trials and 3 prospective studies concluded that oral B12 at 1,000 mcg a day was a safe and effective alternative to intramuscular injections
[DOI] [PMC free article] [PubMed] [Google Scholar] Neumann J
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Inflammation (2019) 42(1):33141
If you dont have access to a fridge (like if youre traveling), its okay to store the pen in a cool, dark place for up to 21 days, keeping it between 46 degrees F and 86 degrees F
Community protocols most commonly describe an 8-12 week injectable course (100-200 mg SC 2-3x/week), with oral NMN (500 mg daily) as a bridge during off periods before repeating