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In research settings, it has demonstrated significant weight reduction in certain patient populations when combined with lifestyle modification

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While these may represent minor side effects, they can also indicate more significant interactions with the medication requiring dose adjustment or additional monitoring

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The arithmetic is straightforward

They suggested that the observed improvement in the neuromuscular function may be due to the increased sarcoplasmic reticulum Ca 2+ release ( supplementation was related to the increase in the tetanic Ca 2+ concentrations (59)