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The pathways that regulate GSH production and recycling are extremely complex [Figure 1], and most research on this system has been conducted through association studies which can suggest local mechanisms but cannot fully capture the interactions in the system as a whole

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Efek samping yang dapat muncul dengan pemberian glutathione IV adalah reaksi pada kulit, nyeri pada area abdominal pada pasien yang diberikan glutathione 2x seminggu, disfungsi tiroid, disfungsi ginjal hingga potensi gagal ginjal, disfungsi hati, dan komplikasi letal seperti emboli udara, infeksi karena darah, dan potensi sepsis karena teknik injeksi yang kurang tepat/steril dengan menggunakan jarum yang tidak steril

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