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GLP-1 might exert a modulatory effect on the release of neurotransmitters such as serotonin and dopamine and on the production of pro-inflammatory cytokines [22]
As part of the incretin hormones, GLP-1 has three known mechanisms of action: activating glucose-dependent insulin secretions, thereby reducing plasma glucose, suppressing glucagon secretion, and delaying gastric emptying [3]
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These typically resolve without intervention and do not necessarily indicate hepatotoxicity
The bottom line At the end of the day, microdosing GLP-1s is just a buzzy way of talking about a different approach to GLP-1s namely, starting (and staying) at the right dose for you, even if its lower than what the manufacturer recommends
Retatrutide is an investigational medication being developed by Eli Lilly and Company for treating obesity and type 2 diabetes
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