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HGH affects growth, metabolism, and body composition

Ronald Hugate et al., The effects of intratendinous and retrocalcaneal intrabursal injections of corticosteroid on the biomechanical properties of rabbit Achilles tendons, The Journal of bone and joint surgery

While generally safe, common B12 side effects include diarrhea and swelling at the injection site

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Appreciation of these issues will determine whether the results of an experiment are relevant for understanding mechanisms of cell death and identification of novel therapeutic targets for most patients or if they are clinically irrelevant and just adding background noise to the literature