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Besides disruption of liver histoarchitecture (including vascular dilation and congestion), hepatocyte degeneration, increased serum AST and alanine aminotransferase (ALT) levels, enhanced oxidative stress, and pronounced infiltration of inflammatory cells accompanied by upregulation of pro-inflammatory genes were observed [151]

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For many patients in Tampa and its surrounding areas, this proven history gives peace of mind, especially compared to newer medications that may still be evolving in terms of understanding long-term effects