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It is helpful in reducing stress and anxiety

Antioxidant is indeed the buzzword of the decade

2 Methodology A comprehensive literature search was conducted to identify published evidence on the chemistry, pharmacokinetics, mechanisms of action, preclinical activity, clinical data, formulations, and regulatory aspects of luteolin in female reproductive disorders

As a reminder, cells face oxidative stress when free radicals outnumber antioxidants capacity to neutralize them

ROS can oxidatively modify regulatory subunits of the IB kinase (IKK) complex, promoting IB phosphorylation and subsequent degradation via the ubiquitin-proteasome pathway, thereby releasing active NF-B dimers (e.g., p50-p65) for nuclear translocation (S-Pessoa et al., 2023

These cascades regulate antioxidant enzymes, such as GPX4, inhibit lipid peroxidation reactions, and suppress tumor cell ferroptosis