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(PubMed) Kuzminski AM, Del Giacco EJ, Allen RH, Stabler SP, Lindenbaum J

This vitamin A based ingredient is the most used and most studied compound for ageing

Serum IGF-1 (insulin-like growth factor 1) is the primary downstream biomarker for CJC-1295 activity

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secondary IR cross-reactivity Key downstream pathways / PI3K-Akt-mTOR and RAS-MAPK-ERK IGF-1 DES comparison / DES is 6-aa truncated, 10x higher potency but even shorter half-life (~20-30 min) Regulatory status / Not FDA-approved for any indication