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BIIB142BIIB142 / IRAK4 / degrader / ImmunologyAutoimmune diseasePhase 1 FelzartamabCD38 / mAb / Rare diseaseAntibody-mediated rejectionPhase 3IgA nephropathyPhase 3Primary membranous nephropathyPhase 3 OmaveloxoloneSKYCLARYS / Nrf2 / activator / Rare diseasePediatric Friedreich ataxiaPhase 3 SalanersenBIIB115 / SMN / ASO / Rare diseaseSpinal muscular atrophyPhase 3 ZorevunersenSCN1A / ASO / Rare diseaseDravet syndromePhase 3 Nusinersen high doseSPINRAZA / SMN2 / splice modulator / Rare diseaseSpinal muscular atrophyApproved in U.S

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