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Lumertz FS, Kestering-Ferreira E, Orso R, Creutzberg KC, Tractenberg SG, Stocchero BA, et al

By 12 months, two more patients discontinued for lower urinary tract symptoms and difficult-to-control hypertension respectively (Supplementary Table 3)

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Mechanism of Action Enzymatic Protection Mechanism : The phenylacetyl group acts as a decoy substrate for glutathione-degrading enzymes, redirecting their activity away from glutathione itself and toward cleaving the protective phenylacetyl modification

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