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To elucidate the potential impact of TTR amyloidosisassociated oxidative stress on GSH homeostasis, we quantified plasma PGA levels in three well-defined cohorts aged 55 years and older: asymptomatic carriers of the TTR-V30M mutation, symptomatic carriers with confirmed TTR amyloidosis (TTR-V30M patients), and healthy controls with the wild-type TTR genotype