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Efficacy and safety of coadministered onceweekly cagrilintide 2.4 mg with onceweekly semaglutide 2.4 mg in type 2 diabetes: a multicentre, randomised, doubleblind, activecontrolled, phase 2 trial

[ CrossRef ] [ PubMed ] Demetriadou C, Koufaris C, Kirmizis A

Mechanisms underlying the anorexigenic effects of dual GIPR/GLP-1R agonists GIPR/GLP-1R dual agonists induce significantly greater weight loss than GLP-1RAs alone in both animal models and human [29, 30]

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In addition, consistent supplementation encourages long term improvement rather than short term change