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Yes circadian-aligned eating improves insulin sensitivity, SCFA oscillation, fat oxidation, and GLP-1 responsiveness

C., Xu, S

While morning and pre-workout timings often provide the most benefit, the right time ultimately depends on your training pattern and how your body feels

Current guidelines recommend GLP-1s for adults with obesity (BMI at or above 30), or adults with overweight (BMI at or above 27) plus a weight-related comorbidity such as type 2 diabetes, hypertension, fatty liver disease, or sleep apnea, for whom the cardiometabolic benefit of the medication exceeds its risks

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It may also be appropriate for those with weight-related health concerns, such as high cholesterol or insulin resistance