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Require In-Person Medical Supervision: Patients with complex medical histories or those who prefer face-to-face clinical relationships may benefit from traditional in-office weight management programs

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As tirzepatide promotes substantial weight reductionclinical trials such as SURMOUNT-1 demonstrated average weight loss of approximately 20.9% of body weight at the 15 mg dose in adults without diabetesthis metabolic shift can influence the hypothalamic-pituitary-ovarian axis that regulates menstruation

The third thing that I hope will evolve is that right now, people do lose a fair amount of muscle weight on this, so theres clearly some work to be done about how you retain muscle mass, which is important, particularly in older populations.

Epidemiologic and economic consequences of the global epidemics of obesity and diabetes