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GLP-1 receptor agonists have been shown in clinical studies to support meaningful and sustained weight loss when used alongside lifestyle changes such as improved diet, regular physical activity, and ongoing medical supervision

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Dogulu CF, Tsilou E, Rubin B, Fitzgibbon EJ, Kaiser-Kupper MI, Rennert OM, Gahl WA (2004) Idiopathic intracranial hypertension in cystinosis

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However, given the autoimmune nature of Hashimotos, its crucial to monitor thyroid function and antibody levels closely when initiating or adjusting Semaglutide therapy