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bioRxiv , 2021.2009.2028.462109 (2021)

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Animal model metabolomics studies reveal that HFD-induced NAFLD is characterized by hepatic saturated fatty acid (myristic acid, palmitic acid) and monounsaturated fatty acid (oleic acid) accumulation, accompanied by decreased gluconeogenic amino acid (glycine, alanine, aspartic acid, glutamic acid, proline) levels (95)

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They might be given every 1-3 months, depending on how the patient is doing and their ongoing needs