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Multiple molecular subtypes of GST have shown the ability to prevent skin, colon, and liver cancer initiation in mice exposed to carcinogens or lacking tumor suppressors (Van Remmen et al., 2003)

However, there is some evidence that the constitutively active Y1253D Met mutation may undergo clonal selection during tumor spreading and metastasis

The chemical reaction that occurs between nitrites and secondary amines can form carcinogenic nitrosamines, which pose a threat to human health 17

Balibar, C

Margis R, Dunand C, Teixeira FK, Margis-Pinheiro M

29 This category of antioxidants is also referred to as the second line of defense