Taken together, these limitations highlight the urgent need for updated frameworks that transcend reductionist approaches and integrate genomic, metagenomic, biochemical, nutritional, and lifestyle dimensions into a comprehensive precision-medicine strategy for neurodegeneration
The dose was well tolerated by the subjects, and a decrease in parameters capturing oxidative stress, an increase in antioxidant capacity and an improvement in glycated hemoglobin (HbA1c) and renal metabolism (alpha-1 microglobulin) were observed [43]
Clinical reviews likewise suggest that GLP-1RA users may develop micronutrient insufficiencies resemblingalthough not identical topatterns observed after bariatric surgery [94, 101, 102]
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10.1016/S0016-5085(25)03109-9 Gastroenterology
