On the other hand, it is not clear whether FasL induces the formation of this complex, since it was reported that its activation was ROS-dependent and ligand-independent due to the inability of Fas agonists to activate caspase-8 and trigger cell membrane scrambling in mature RBCs [192]
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Even at trace concentrations, ranging from nanograms to micrograms per liter, these compounds can disrupt microbial ecosystems, reduce the efficacy of WWTPs, and promote the selection and propagation of antimicrobial resistance genes (ARGs) [85]