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Differential involvement of mitochondrial dysfunction, cytochrome P450 activity, and active transport in the toxicity of structurally related NSAIDs

[DOI] [PMC free article] [PubMed] [Google Scholar] 99.Angarita G.A., Matuskey D., Pittman B., Costeines J.L., Potenza M.N., Jastreboff A.M., Schmidt H.D., Malison R.T

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But this study introduces genuine doubt about whether the theoretical synergy between phentermine and incretin-based drugs translates into real-world clinical benefit

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Targeting Co-Regulatory Feedback Loop of MYC and GSPT1 By MYC/GSPT1 Dual Degradation Is Synthetic Lethal in Combination with Ven/Aza in TP53 Mutant Acute Myeloid Leukemia Stem and Progenitor Cells