Semaglutide has a half-life of one week compared to liraglutides 13 hours, allowing for once-weekly (instead of daily) injections
This may be more likely to occur in patients who have a family history of heart disease
Difficulty breathing or swelling of the lips, tongue, or throat, which may signal a severe allergic reaction (anaphylaxis)
Specific warning signs that require prompt medical assessment include: Symptoms suggesting nocturnal hypoglycaemia (night sweats, palpitations, confusion upon waking) Signs of pancreatitis (severe, persistent abdominal pain that may radiate to the back, accompanied by vomiting) [16] [1] Other severe gastrointestinal complications (persistent vomiting, signs of dehydration) Mental health concerns such as significant anxiety, depression, or mood changes Patients with pre-existing sleep disorders, such as sleep apnoea or insomnia, should inform their healthcare provider before starting Wegovy, as weight loss may improve these conditions but the medication could theoretically interact with existing sleep problems
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Krasnyi, A
