in patients with T2DM (38) found that continuous GLP-1 administration via a subcutaneous pump to raise serum GLP-1 levels from a mean of 9.7 pM at baseline to 282 pM over 6 weeks significantly reduced plasma glucose concentrations, improved glycated hemoglobin, and enhanced insulin sensitivity and -cell function compared to placebo, with no significant limiting side effects reported
SREBP-1c mRNA (lipogenic transcription factor
eLife 12, RP92362
(12) found that anthraquinone laxative can enhance cell proliferation activity, inhibit cell apoptosis, and may promote cell carcinogenesis
Zhang L, Jiang L, Yu L, Li Q, Tian X, He J, et al
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