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Schizophrenia The hypothesis that there might be a relationship between the disorders of 1-carbon metabolism (and transmethylation) with the genesis of psychiatric disorders was first forwarded by Smythies as early as 1963 [107]

Patients following such a diet, should be advised to take oral vitamin B 12 regularly

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They successfully attached various aminooxy tags to the acetone linker, including fluorophores like Alexa Fluor 488 and Alexa Fluor 647