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Another study confirmed the anti-IgE effects of arctigenin, whereby arctigenin (10 6 , 10 5 , and 10 4 mol/L) inhibited -hexosaminidase release, histamine release, and IL-4 production of RBL-2H3 cells with no evident cytotoxicity [84]

Both are well-tolerated with minimal side effects

Therefore, pyruvate promotes gentamicin influx and thereby reverses gentamicin resistance

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doi: 10.3803/EnM.2021.1109 110 ClausenCLRasmussenKJohannsenTHHilstedLMSkakkebkNESzecsiPBet al

Treatment may include personalized dietary modifications, supplementation, gut healing protocols, elimination of trigger foods, sleep optimization strategies, and environmental changes to reduce toxin exposure