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BOC Sciences' Solution Developed a high-stability lipid composition incorporating saturated phospholipids and cholesterol to improve bilayer rigidity

Additionally, the N-terminal extension may partially shield protease-sensitive sites on the IGF-1 backbone from insulin-degrading enzyme (IDE) and other endopeptidases

Pharmacologically this yields a highly selective GHS-R1a agonist which, in classical rodent studies (Raun et al., Eur J Endocrinol 1998), does not significantly elevate cortisolemia, ACTH, prolactin or FSH/LH at effective doses, unlike GHRP-2 and GHRP-6

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Each vertex of this triangle communicates with and amplifies the other two

10 Because PepT1 is upregulated in inflamed colon, this offers a plausible route for targeted delivery to inflamed gut tissue