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Although interventions such as antihypertensive therapy and valve replacement can resolve chronic cardiac injury, they often fail to reverse the myocardial fibrosis process, suggesting that the fibrogenic process may become self-sustaining
McMinn J, Wilkinson C, Havel P, Woods S, Schwartz M
The mechanism was proposed to involve copper-dependent enzymes (notably lysyl oxidase, which catalyzes the cross-linking of collagen and elastin and requires copper as a cofactor), GHK-specific effects on growth factor activity, and downstream gene-expression effects in fibroblasts and other tissue-repair-relevant cell types
GLP-1 medications such as Ozempic, Mounjaro and Wegovy have become extremely popular options for managing c
doi: 10.2174/1568026615666150813142215 268 SukT