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In adipocytes, GPR81 acts synergistically with insulin to lower intracellular cyclic adenosine monophosphate (cAMP) levels, thereby suppressing postprandial lipolysis (52)

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4 In blood diseases like leukemia, polycythemia vera and hypereosinophylic syndrome, the cause is often an enhanced production of the transport protein haptocorrin, to which most of the circulating B12 in blood is bound