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His is vital for hemoglobin synthesis (37), and Cr metabolism may influence His methylation via methyl group donation (e.g., 3-methylhistidine formation) (38), thereby regulating milk His levels
Spleen tyrosine kinase signaling in myeloid cells promotes macrophage infiltration, glomerulosclerosis and interstitial fibrosis in diabetic kidney disease
Figure 5 3.5.6 Potential clinical value Given their multitargeted mechanisms and low toxicity profiles, ITCs are actively explored in clinical settings as chemopreventive or adjunct therapeutic agents (128)
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