Tatone C, Amicarelli F, Carbone MC, Monteleone P, Caserta D, Marci R, et al
Safety analysis will be performed on the ITT analysis set
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Continuing their research on effective persulfide prodrugs, these authors next synthesized a small molecule which acts as an NAC-SSH donor in response to esterase and termed it ester disulfide prodrug, EDP-NAC
Furthermore, experimental studies have demonstrated that TMAO exacerbates the progression of aortic dissection by inducing endothelial dysfunction and inflammation, primarily through activation of the NF-B signaling pathway [38, 65]
PrecisionLifes platform finds more pathways and applies mechanistic patient stratification, identifying the specific combinations of genetic and biological drivers that create different subgroups within a disease