tirzepatide 25 In adults with obesity but not diabetes, leads to significantly greater weight loss than semaglutide over 72 weeks, and nearly double the patients on tirzepatide meet the 25% weight-loss target. http://ms.spr.ly/6183SkuIL 149.00 | Tirzepatide --- 27

It is a physician-guided program that combines medication, lifestyle support, and ongoing monitoring to help patients lose weight safely and effectively

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In patients with obesity and heart failure with a preserved ejection fraction included in the STEP-HFpEF trial, semaglutide significantly reduced symptoms, improved physical limitations, and enhanced exercise functions compared to placebo (89)

A randomised clinical trial in JAMA Psychiatry (2025) found semaglutide significantly reduced alcohol craving and consumption in patients with alcohol use disorder

Tirzepatide produces greater average weight loss than semaglutide in head-to-head clinical trials, but that single fact does not settle the choice for every patient

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