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Dual GLP-1/GIP agonist tirzepatide has exhibited impressive histological benefits including both MASH resolution and fibrosis improvement rates exceeding 50% in phase 2 studies

Eur J Med Chem

At 4mg, rates ranged from 18% to 36%

*Correspondence: Lishou Xiong, [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Microbiome in Health and Disease, a section of the journal Frontiers in Cellular and Infection Microbiology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

In addition to reductions in binge-related behaviors, emotional eating a tendency to eat in response to negative emotions was moderately decreased among those treated with GLP-1RAs

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