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10.1016/j.amjcard.2021.01.017 62 InoueK.FujieS.HasegawaN.HoriiN.UchidaM.IemitsuK.et al (2020)

Retatrutide, a triple-receptor agonist still in Phase 3 clinical trials, has posted some of the most impressive weight loss numbers ever recorded in obesity research, hitting 24.2% body weight reduction in 48 weeks

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To date, mechanistic studies that evaluate gastric emptying in patients chronically exposed to pharmacological doses of GLP-RAs have produced extremely variable and often poor-quality results

Simply put, Semaglutide GLP-1 increases digestion time, helping you feel fuller for longer