The potential benefit of these changes was offset by a 4.8% increase in apoB (and LDL-C increase by 12%)
It is an extremely powerful antioxidant and in fact has been called the mother of all antioxidants
Conversely, at high concentrations under direct exposure conditions, its iron-chelating properties become predominant, leading to a functional iron deficiency that specifically impairs mitochondrial Fe-S cluster proteins, resulting in an energy metabolism crisis and cell cycle arrest
Schizophr Bull 25 : 763775
Selank works through a different axis
When glutathione levels are depleted - as they consistently are in Hashimoto's thyroiditis, Graves' disease, and hypothyroidism - the consequences cascade: oxidative thyroid damage, protein modification, autoantigen formation, immune activation, and progressive thyroid destruction