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This is probably an underestimate, as many case reports failed to indicate any specific medical management

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Its clinical development for obesity was discontinued in 2007 after the pivotal 536-participant Phase IIb trial failed to meet its primary efficacy endpoint, and no formulation of the compound has received FDA approval since

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For the cardiovascular risk-reduction indication, the lifestyle-program participation requirement is generally waived, making that PA path somewhat faster for qualifying members