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Cognitive impairment, ranging from mild cognitive dysfunction to Parkinsons disease dementia (PDD), affects up to 80% of individuals in advanced stages (25)

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Moreover, a meta-analysis showed that the addition of STS seemed more effective in treating heart failure than Western medicine alone [153]

JAK are a part of the JAK/STAT pathway, and this signaling is continuously activated, resulting in the elevated level of MMPs and apoptotic chondrocytes in RA synovial joints (130)

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