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Interestingly, IPA software predicted an inhibition of oxidative phosphorylation in metformin treated SW837 cells, supporting the demonstrated metformin-induced inhibition of OCR using Seahorse live-cell metabolic profiling ( Figure 1 )

5 Khavinson V.Kh., Bondarev I.E., et al

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The control of ROS levels in cells is crucial for cellular homeostasis, as Moderate ROS levels in cells can serve as signaling molecules, but excessive ROS production can lead to damage to DNA, proteins, and lipids [2]