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Both semaglutide (Ozempic/Wegovy) and tirzepatide (Mounjaro) were developed to treat diabetes and were later found to be highly effective for weight loss

doi: 10.1097/brs.0000000000000972 119 SeverinsenMCKPedersenBK

Neuroinflammation is the second major target

Compounded Semaglutide & Tirzepatide the most prescribed GLP-1s in clinical weight loss Month-to-month Cancel anytime HSA/FSA accepted Takes 90 seconds 100% Private Free Weight loss isn't just about eating less

GLP-1 exerts its effects through GLP-1R, a member of the class B G protein-coupled receptor family, mainly by activating the cAMP-protein kinase A (PKA) pathway to promote insulin release and improve insulin resistance (30,36)

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