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Measurements of worse eyes were used for statistical analysis, i.e., higher pRNFL thickness as a marker of oedema and lower GCL volume as a marker of neuroaxonal loss

Selective therapeutic targeting of tumor-derived cells expressing Tie-2 could disrupt the vasculature and eradicate the tumor, leading the authors to conclude that glioma stem cell derived endothelial cells contributed to vascularization of glioma [59]

2025;8(1):e2457232

PMID: 3753594

No clinical follow-up: Side effects, dose escalation, and treatment monitoring require ongoing prescriber involvement

50.5% lost 15% or more of their body weight compared to 4.9% of the placebo group