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We next explored the broader metabolic impact of 5FU in these drug-tolerant cells

doi: 10.1016/j.amjmed.2025.01.021 5 NauckMAMeierJJ

Although the exact mechanism of cyclosporine nephrotoxicity remains unknown, its administration has been associated with in vivo reduction of GSH concentrations in the livers and kidneys of rats, which may be related to adverse effects of this immunosuppressive agent