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Hepatoma cell lines, such as HepG2, in general display lower expression levels of hepatic phase I and phase II enzymes compared with primary hepatocytes, thus questioning their informative value for the situation in vivo

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Reductions of glycemic index and hyperinsulinemia by GLP-1 GLP-1 exerts an important effect directly on the brain, and this effect is probably even more important for the analogues than for the endogenous GLP-1 released after ingestion of protein and fat

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