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Biochem Biophys Res Commun 298:779784 Maida A, Lamont BJ, Cao X, Drucker DJ (2011) Metformin regulates the incretin receptor axis via a peroxisome proliferator-activated receptor alpha-dependent pathway in mice
The thigh is one of the most accessible and effective injection sites for weekly GLP-1 therapy, offering a large surface area for proper site rotation
10.1038/342440a0 Nature 130 NaldiniL.TamagnoneL.VignaE.SachsM.HartmannG.BirchmeierW.et al (1992)
MDPI The Metabolic and Endocrine Effects of a 12-Week Allulose-Rich Diet The global rise in type 2 diabetes (T2D) and obesity necessitates innovative dietary interventions
A phase 3 study (Identifier: NCT02187003) to evaluate the efficacy and safety of rivipansel in the treatment of VOC in hospitalized patients with SCD was terminated (posted on ClinicalTrials.gov February 20, 2020) based on failure of the primary study (NCT02433158) to meet the study efficacy endpoints of time to readiness-for-discharge
Additionally, blood was collected from cardiac puncture for pharmacokinetic analysis 24 h after the last injection
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