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Nonetheless, oxidative stress, as measured by 8-hydroxy-2-deoxyguanosine (8-OHdG), further showed that PCC samples had significantly higher levels of DNA damage, compared with convalescent individuals

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It has been shown that TMAO (demethylated to produce formaldehyde) induces -cell dysfunction and type 2 diabetes in mice via NLRP3 inflammasome activation and calcium transients [22]

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