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Critically, such integration facilitates the identification of dynamic biomarkers and the development of personalized therapeutic regimens, including senolytic cocktails and metabolic reprogramming strategies
In rat pinealocytes (the melatonin-producing cells of the pineal gland), Epitalon was shown to upregulate both AANAT (arylalkylamine N-acetyltransferase, the rate-limiting enzyme in melatonin production) and pCREB (a transcription factor involved in melatonin gene expression)
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