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1,2,6,18 The recommended laboratory evaluation for patients with suspected vitamin B 12 deficiency includes a complete blood count and serum vitamin B 12 level

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In view of this continuity, the following discussion traces these events as a mechanistic cascade, starting with defective ERmitochondria calcium coupling, continuing through redox injury and impaired mitochondrialysosome quality control, and then considering interfaces that govern polarity, metabolism, transcriptional adaptation, and inflammatory amplification

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