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Most significantly for PCOS, this list includes: Insulin and oral hypoglycemics

Some patients or prescribers may be tempted to accelerate this process, but doing so often leads to intolerable nausea and vomiting, potentially causing treatment discontinuation before therapeutic doses are reached

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Mice are treated daily, for 3 consecutive days, on the dorsum of both ears with the test material or with an equal volume of vehicle alone